Methotrexate-Related Pancytopenia: A Case Report
نویسندگان
چکیده
منابع مشابه
Methotrexate Induced Pancytopenia
The well-reported methotrexate (MTX) toxicities are based on the duration and cumulative dosing of drug. The typical toxicities can be predicted by the timing of drug administration, where mucositis occurs as an earlier effect, while myelosuppression and the sequelae of pancytopenia occur later after MTX administration. Despite these well-known toxicities, low dose MTX therapy can become proble...
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Background: Methotrexate is an anti-metabolite drug and one of the folic acid analog that it can play an important and functional role in the treatment of many malignancies and inflammatory diseases. However, the development of petechiae (maculopapular rash) is a very rare complication. Case Presentation: The patient was a 77 years old woman, Aryan race, who was known a case of severe and prog...
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Vancomycin is the first-line agent for the treatment of bacteremia, endocarditis, pneumonia, cellulitis, and osteomyelitis. Pancytopenia is an uncommon adverse effect of vancomycin therapy, with only a few cases of vancomycin-related neutropenia and pancytopenia described in the literature. We describe a case of a 56-year-old man who was diagnosed with chronic paraspinal abscess and started on ...
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Pancytopenia in childhood can be caused by a variety of underlying diseases including hematological and non-hematological entities. Phenylketonuria (PKU) is an inborn error of phenylalanine metabolism. No association between PKU and pancytopenia has ever been reported. We report the first case of PKU revealed by a pancytopenia at presentation. The patient was an infant girl born to healthy non-...
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Although the most common hematological disturbance in thymoma is pure red cell aplasia, pancytopenia is a very rare paraneoplastic syndrome in this disorder. We only found one case in literature reviews. We report a 36 year old female with an anterior mediastinal mass and severe pancytopenia. With a mediastinotomy incision, biopsy of the tumor was obtained. The report of the pathologist was t...
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ژورنال
عنوان ژورنال: Journal of Cardiac Critical Care TSS
سال: 2019
ISSN: 2456-9224
DOI: 10.1055/s-0039-3402326